AID
|
|
Set
|
|
Target
|
|
Ligands
|
|
Actives
|
|
Inactives
|
|
PDB templates
|
492947
|
|
ADRB2
|
|
Beta2 adrenergic receptor
|
|
Agonists
|
|
17
|
|
312483
|
|
8
|
1030
|
|
ALDH1
|
|
Aldehyde dihydrogenase 1
|
|
Inhibitors
|
|
7168
|
|
137965
|
|
8
|
743075
|
|
ESR_ago
|
|
Estrogen receptor α
|
|
Agonists
|
|
13
|
|
5583
|
|
15
|
743080
|
|
ESR_antago
|
|
Estrogen receptor α
|
|
Antagonists
|
|
102
|
|
4948
|
|
15
|
588795
|
|
FEN1
|
|
FLAP Endonuclease
|
|
Inhibitors
|
|
369
|
|
355402
|
|
1
|
2101
|
|
GBA
|
|
Glucocerebrosidrase
|
|
Inhibitors
|
|
166
|
|
296052
|
|
6
|
602179
|
|
IDH1
|
|
Isocitrate dihydrogenase
|
|
Inhibitors
|
|
39
|
|
362049
|
|
14
|
504327
|
|
KAT2A
|
|
Histone acetyltransferase KAT2A
|
|
Inhibitors
|
|
194
|
|
348548
|
|
3
|
995
|
|
MAPK1
|
|
Mitogen-activated protein kinase 1
|
|
Inhibitors
|
|
308
|
|
62629
|
|
15
|
493208
|
|
MTORC1
|
|
Mechanistic target of rapamycin
|
|
Inhibitors
|
|
97
|
|
32972
|
|
11
|
1777
|
|
OPRK1
|
|
Kappa opioid receptor
|
|
Agonists
|
|
24
|
|
269816
|
|
1
|
1631
|
|
PKM2
|
|
Pyruvate kinase muscle isoform 2
|
|
Inhibitors
|
|
546
|
|
245523
|
|
9
|
743094
|
|
PPARG
|
|
Peroxisome proliferator-activated receptor γ
|
|
Inhibitors
|
|
27
|
|
5211
|
|
15
|
651631
|
|
TP53
|
|
Cellular tumor antigen p53
|
|
Inhibitors
|
|
79
|
|
4168
|
|
6
|
504847
|
|
VDR
|
|
Vitamin D receptor
|
|
Inhibitors
|
|
884
|
|
355388
|
|
2
|